CONOLIDINE ALKALOID FOR CHRONIC PAIN NO FURTHER A MYSTERY

Most recently, it has been discovered that conolidine and the above derivatives act over the atypical chemokine receptor 3 (ACKR3. Expressed in comparable parts as classical opioid receptors, it binds into a wide array of endogenous opioids. As opposed to most opioid receptors, this receptor functions as being a scavenger and does not activate a 2n